ALTERATIONS IN GERMINAL CENTER FORMATION AND B CELL ACTIVATION DURING SEVERE ORIENTIA TSUTSUGAMUSHI INFECTION IN MICE.

Alterations in germinal center formation and B cell activation during severe Orientia tsutsugamushi infection in mice.

Scrub typhus is a poorly studied but life-threatening disease caused by the intracellular bacterium Orientia tsutsugamushi (Ot).Cellular and humoral immunity in Ot-infected patients is not long-lasting, waning as REANIMATING MIST early as one-year post-infection; however, its underlying mechanisms remain unclear.To date, no studies have examined ge

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